![]() Serious side effects of MifepristoneĪlong with its needed effects, mifepristone may cause some unwanted effects. Before prescribing mifepristone, advise the patient about these serious risks, ensure that she knows what to do if she experiences symptoms of these events, and discuss the medication guide and the patient agreement with her. Mifepristone is only available through a restricted program called the mifepristone REMS Program. Bleeding: Prolonged heavy bleeding may be a sign of incomplete abortion or other complications and prompt medical or surgical intervention may be needed. ![]() Atypical Presentation of Infection: Patients with serious bacterial infections and sepsis can present without fever, bacteremia or significant findings on pelvic examination use a high index of suspicion to rule out serious infection and sepsis. Mifeprex®: Serious and sometimes fatal infections and bleeding occur very rarely following spontaneous, surgical, and medical abortions, including following mifepristone use. Pregnancy should be prevented during treatment and for one month after stopping treatment by the use of a nonhormonal medically acceptable method of contraception unless the patient has had a surgical sterilization. Pregnancy must therefore be excluded before the initiation of treatment or if treatment is interrupted for more than 14 days in females of reproductive potential. Korlym(TM): Mifepristone has potent antiprogestational effects and will result in the termination of pregnancy.
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